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1633S-1639S, Oct

They found elevated ROS biomarkers and an AGE-mediated activation of proinflammatory pathways, as indicated by an activation of the AGE-RAGE-NFBp65 pathway in DPN [71]

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However, these drugs act mainly on the upstream signaling of autophagy pathways and enhance autophagy while also playing a role in other pathways, such as apoptosis, the immune response and cell growth, which can lead to side effects
