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Silymarin typically has no side effects, but consider drug interactions in polymedicated patients, such as the following: antiviral drugs, drugs affected by cytochrome P450 & CYP3A4 inhibition and drugs cleared via hepatic glucuronidation

M.RamasamyK.LimS
9,16 10.3389/fmed.2022.1033272 [DOI] [PMC free article] [PubMed] [Google Scholar] 78.Sang S., Pan X., Chen Z.et al

Mayo Clinic: There's no solid proof that vitamin B-12 shots, also called injections, help you lose weight
