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Cell doublings were normalized to the average of the SLC25A39 knockout cells expressing SLC25A39 cDNA

Sousa-Lima I, Fernandes AB, Patarro RS, Kim Y-B, Macedo MP

Therefore, inhibition of the cysteine cell transporter system xc (cystine/glutamate antiporter protein SLC7A11) can lead to GSH depletion and cell death through ferroptosis

NAD + precursors include both natural and synthetic compounds that can modulate the NAD + pool via the above-mentioned biosynthesis pathways in the NAD + homeostasis section
