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Description
Xu, E., Xie, Y
MCI, Mild Cognitive Impairment
Furthermore, the acetyl-CoA derived from carnitine has been also reported to regulate gene expression by influencing histone acetylation (Madiraju et al., 2009)
The pathways of programmed cell death, SIRT1, AMPK, and WISP1 offer exciting prospects for maintaining metabolic homeostasis and nervous system function that can be compromised during aging-related disorders and lead to cognitive impairment, but these pathways have dual roles in determining the ultimate fate of cells and organ systems that warrant thoughtful insight into complex autofeedback mechanisms
