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Immune suppressive mechanisms in the tumor microenvironment

Xu receives research funding and serves on an advisory committee for GlaxoKlineSmith

Furthermore, compared to healthy tissue-derived MSCs, tumor tissue-retained MSCs were found to exhibit unique expression profiles and significant tumor-promoting properties (125)
Metabolic flexibility or adaptation by cancer cells, as well as reduced antitumor immunity, may be unwanted consequences of inhibiting glutamine metabolism
