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Although HQ is the gold standard and the most commonly prescribed depigmenting agent for melasma management, its effects may be reversible and concerns regarding its adverse reactions including skin irritation, erythema, contact dermatitis, hypochromia, nail discoloration, and ochronosis persist 21

[DOI] [PubMed] [Google Scholar] 101.Anurathapan U., Pakakasama S., Mekjaruskul P., Sirachainan N., Songdej D., Chuansumrit A

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Reactive Sulfur-Containing Fragments Generated by -Lyase Reactions Involving Halogenated Alkene Cysteine S -Conjugates A few examples will be provided here
