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Strategies aimed to increase cytosol GSH (e.g., NAC) may not be an optimal approach for boosting mGSH and therefore for treatment of SH or AD, as it would result in mainly increasing cytosol GSH without replenishing mGSH levels A new approach has been exploited recently in several contexts by the development of a series of cationic antioxidants targeted to mitochondria, including derivatives of the endogenous antioxidants ubiquinol (MitoQ), alpha-tocopherol (MitoVit E), and of the synthetic spin trap PBN (MitoPBN

Pernicious anemia is an autoimmune disease that attacks and potentially destroys gut cells so that intrinsic factor is not present, which is crucial for vitamin B12 to be absorbed

Per-month math, because thats how patients think

Molecules 19 (1), 291305