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Treatment of persistent sleep-wake schedule disorders in adolescents with methylcobalamin (vitamin B12) The improvement of the sleep-wake rhythm disorders appeared immediately after the administration of high doses (3,000 micrograms/day) of methylcobalamin
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However, to lesser degrees, intravenous, intramuscular, intrabronchial (i.e., nebulized), and intranasal glutathione administrations have all been used to increase circulating or tissue-specific GSH levels
