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Despite the low sequence identities, all cytosolic GSTs share a common fold, which is also largely conserved in mitochondrial GSTs (Fig
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Adipocyte specific KO of ABHD5 decreased lipolysis, resulting in reduced FA flux to the liver, and protection against HFD induced hepatic steatosis (149), suggesting that suppressing adipocyte lipolysis could be protective against FLD
Longo, M
