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Pyr-sulf pre-incubation was ineffective in altering t -BHP induced changes in -III tubulin levels (Fig

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To evaluate the feasibility of direct modification of an AON with activated furan towards a 5HP2O bearing ONbased on the modular three-step one-pot synthetic procedure, we decided to perform the first two steps as previously described (1 mmol substituted furan, 83 mM, see Supplementary Scheme 1) and then dilute the reaction mixture to a concentration which is relevant for AON modification (40 nmol AON, 100200 M)

Reconstitution: 3.0 mL per 1 mg vial (~0.333 mg/mL or 333 mcg/mL) for precise unit measurements