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The peptide influences laminin-5 (LN-5) expression in a temporally sophisticated mannerinitially inhibiting LN-5 to promote cellular proliferation and differentiation, then upregulating LN-5 expression during middle and late healing stages to improve the matrix environment and promote epidermal cell migration

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So far, the experimental search of muscle reattachment following surgical detachment comprises only one monkey study, where the detached temporal muscle became (after 8 weeks) similar to its normal state in a process similar to conditions that initiate bone remodeling and bone graft replacement [18]