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In plants, a single copy gene for TPST has been found to have no similarity to cytoplasmic SOTs and no similarities to TPST from yeast or animals (Komori et al., 2009)
10.1021/acs.jafc.4c03546 51
Chelating Effect of SAC and AGE Divalent metals (zinc, iron, copper, cobalt, manganese) are involved in a considerable number of physiological processes
Since the presence of GPX4 U46C renders cells inherently sensitive to peroxide-induced ferroptosis, Gpx4 U46C animals showed a significantly shorter survival time after renal IRI compared to wildtype animals, accompanied by increases in serum creatinine and urea values, tubular damage scores and 4-HNE positivity [73]
