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Description
doi: 10.3389/fimmu.2019.00009
Skin mast cells carry MRGPRX2, a receptor that fires on cationic, aromatic ("cationic amphiphilic") molecules and releases histamine redness, swelling, the classic wheal. It is confirmed for SS-31, which activates the receptor well below its injection concentration
Atyabi N, Poorkabir M, Jebeli javan A, Afshar M
There have been reports of glutathione causing changes in skin pigmentation
