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doi: 10.1002/biof.1513

Kla specifically activates immune checkpoint (including PD-L1), oncogenes, factors linked to the epithelial-mesenchymal transition (EMT), and drug resistance gene transcription programs, all of which completely alter the drug-resistant phenotype of cancer cells

COX17 is another chaperone for copper and it is widely believed that most mitochondrial copper is delivered by this protein [132]

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