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Impaired Detoxification : Lower glutathione levels can hinder the bodys detoxification processes, making it more challenging to eliminate toxins and waste products
A later ANDA filing also positions the company to launch into a genericized market once the 180-day period expires, which may still be commercially attractive for a drug with high volume even at low margins

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On the other hand, GH via its stimulation of local IGF-I is important for testicular production of testosterone and spermatogenesis (79), and the local IGF-IGFBP-axis is involved in selection and growth of the primary follicle in the ovary, estradiol production and ovulation (80, 81)