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A 60% decline over four decades

Gastrointestinal malabsorption: Patients with Crohns disease, celiac disease, gastric bypass or intestinal surgery often cant absorb B12 properly
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Further supporting the importance of arnT , a deletion mutant study in Salmonella Typhimurium (JOL2943) demonstrated that loss of arnT leads to significantly reduced resistance to PMB, impaired intracellular survival, diminished biofilm and swarming capacity, and lower induction of cytokines such as IL-1 in host cells
