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Feb 2015;33(2):179-185
3.1 Oxidative stress Oxidative stress occurs when the physiological equilibrium between oxidation and antioxidation is disrupted, resulting in a shift toward excessive oxidation
307 Besides, lactate and H+ ions exported to the TME impair immune surveillance of effector T cells and NK cells by respectively inhibiting glycolytic flux, granzyme B and IFN- secretion
Many preclinical studies have shown that ROCK inhibitors alleviate pulmonary fibrosis through a variety of potential mechanisms [201]
