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Coniferyl ferulate blocks the NMDAR/NR2B-CaMKII-MAPKs signaling pathway, inhibits ROS production and mitochondrial apoptosis, while reshapes the intestinal microbiota and microbial metabolism, ameliorates colonic inflammation and alleviates depressive symptoms in mice

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Beyond their role in NO metabolism, NO 3 -reducing bacteria also contribute to oral health by metabolising lactate and producing ammonia [76]
