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Esculetin as a coumarin compound in various plants exhibited strong anti-inflammatory effect, reduced the levels of IL-1, IL-6, and TNF- in serum and hippocampus, and down-regulated the hippocampal expression of iNOS and COX-2 in LPS-depressed mice (91)
USA) 74
Neurochem Res 48(3):713724
Enhanced Skin Firmness & Elasticity: Supports collagen production for firmer, more youthful-looking skin
