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There are remarkably few pharmacological interventions that actively promote brain repair after the acute phase stabilizes
Individualization should consider renal function, metabolic demand, and concurrent protein sources
Since a loss of DAPI signal is also observed with nitrofurantoin, which does not bind to DNA but disperses the nucleoid in a similar manner as Cu 3 -TC-Py, nucleoid fragmentation is a considerably more likely explanation for the dispersed DAPI signal and the loss of protein localisation than competition between DAPI and Cu 3 -TC-Py for the minor groove, although it cannot be excluded that the latter may partially contribute to the reduced DAPI signal

10.1053/j.gastro.2017.01.055 29 ChenQ.ZhangH.CaoY.LiY.SunS.ZhangJ.et al (2017)
