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Description
Unlike standard cytoprotective agents that exhibit only prophylactic effectiveness (shared limitation of activity) [41,42,43,44,45,46,47,48], BPC 157 represents a prototype of a more effective class of cytoprotective agents with both prophylactic and therapeutic ability [3,4,5,6,7,8,9,10,11,12,13,14,16,17,18,19,20,21,22,23,24,27,28,29,30,31,32,34,37,39,40]

Related molecular mechanism studies using immunohistochemistry and Western blot analysis revealed significantly decreased GPX4 protein levels and upregulated pro-ferroptotic proteins ACSL4 and p53 in the OA cartilage layer

| nine-amino-acid chain

Pathophysiological changes in astroglia can be primary or secondary and can result in gain or loss of functions
