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Medicine 81 , 122138 (2002)

Secretion of Rhoptry and dense granule effector proteins by nonreplicating Toxoplasma gondii uracil auxotrophs controls the development of antitumor immunity

483,484 The peptide p5RHH has been efficiently used to transfect siRNA and mRNA into human cartilage to reduce chondrocyte apoptosis and prevent cartilage degeneration 485,486,487 as well as into cardiac tissue for treating abdominal aortic aneurysm to reduce the risk of aortic rupture and sudden death in mice

The key to fighting this harmful inflammatory response resides in: (i) addressing the mechanism of the virus penetration into the cell, mediated by binding to and inactivation of the ACE2 protein