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These changes in skin tone can appear gradually and may take time to fade
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doi: 10.1016/j.cell.2009.06.015 126 LeeAJAshkarAA
10.1007/s00106-019-0663-1 HNO 42 LeeJ.PussegodaK.RassekhS.MonzonJ.LiuG.HwangS.et al (2016a)
