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Description
John's wort, a supplement Tryptophan, a supplement Antidepressant medications are a concern because of a complication called serotonin syndrome

Where does the truth lie

Like other lipophilic acids, its main mechanism is the inhibition of the PMF (Levin and Freese, 1977)

Preclinical studies demonstrate biologic activity relevant to tissue repair, supporting biologic plausibility but not clinical effectiveness
