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However, the genetic insertion approach can be very challenging with some antigens

Adropin mediated AKT activation reduces FOXO3a levels, thereby inhibiting oxidative stress and mitochondrial damage [164]

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Based on this evidence, the principle of senolytic approaches is to target Senecent Cell Anti-Apoptotic Pathways (SCAPs) by inhibiting or activating proteins which regulate this apoptosis resistance 8,9
