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Description
The deletion of C/EBP in mouse keratinocytes resulted in increased expression of X-linked inhibitor of apoptosis-associated factor 1 (Xaf1) a pro-apoptotic ISGS that has a role in mediating TNF-induced extrinsic apoptosis (Straszewski-Chavez et al., 2007
In ALS populations, change in HHD scores was correlated with ALSFRS-R and vital capacity (VC), with coefficient of variation performing better than VC, but not as well as ALSFRS-R [47]
[PubMed: 10748217] 432
Although the weight of the liver increased, the hepatocytes did not divide and regenerate and the liver function remained very low
