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Description
Modification in the circulation: As VLDLs pass through the circulation, TAG is degraded by LPL, causing the VLDLs to decrease in size and become denser
Clinical evidence further supports this bidirectional interaction
This leads to an elevation in the level of reactive oxygen species (ROS) in neurons, which subsequently results in dysfunction of the ubiquitin-proteasome system (Martin et al., 2012)
