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Of note, the MAS is composed of 200 mM mannitol, 70 mM saccharose, 10 mM KH 2 PO 4 , 5 mM MgCl 2 , 2 mM K-HEPES, 1 mM K-EGTA, and 0.2% BSA in 200 mL of ultrapure water [24]

3 The mechanism of ferroptosis Ferroptosis is a nonapoptotic and iron-dependent form of cell death closely related to abnormal cellular energy metabolism induced by the toxic accumulation of lipid peroxides on cellular membranes

Pseudo first order rate constants, as determined by MALDI-TOF MS, were 1.65 0.22 min 1 for papain, 0.13 0.014 min 1 for fRMsr, and 0.003 0.0004 min 1 for C165S AhpC