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Description
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Vitamin B12 deficiency manifests itself with the following common symptoms: Failure to grow in puppies and young dogs Weight loss Chronic diarrhea Vomiting Low red blood cell count (anemia) Weakness or other nervous system abnormalities Many of these are similar to symptoms seen in the digestive disorders which lead to B12 deficiency
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In diet-induced obesity (DIO) models, NNMT loss-of-function and selective small-molecule inhibitors reduce white adipose mass and improve metabolic parameters without overt toxicity, positioning NNMT as a tractable target for metabolic-disease research [24]
