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Aceptado: 12-05-2011 INTRODUCTION Melanosis is a term given to lesions showing an increased number of normal melanocytes confined to the basal layer of the squamous epithelium in which the pigment melanin is confined and on visual inspection it may have an appearance similar to malignant melanoma (1, 2)

An imbalance between these opposing events alters mitochondrial dynamics, affects the overall mitochondrial shape, and deregulates mitochondrial function [49]

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