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Description
Epigallocatechin-3-gallate(EGCG)is a polyphenol compound in green tea and is also a natural antioxidant

IFX inhibited the expression of HDAC6 and HDAC7 which are associated with inflammation and cartilage degradation, while enhancing HDAC4 expression, which negatively regulates Runx2 , decreased the activation of NF-B, Jun N-terminal kinase (JNK), and ERK

Bridging this translational gap will require rigorous clinical validation, improved delivery strategies, and careful regulatory frameworks to ensure safe and effective integration of peptide therapeutics into musculoskeletal medicine

According to the findings, copper chelators and copper transporter protein inhibitors significantly reduced neuronal cell mortality, ameliorated neurocognitive deficits, and averted A deposition [83, 84]
