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For tennis elbow, golfers elbow, and other elbow tendon injuries, typical research protocols use 0.25 to 0.5 mg daily via subcutaneous injection near the injury site for 4 to 8 weeks

This may explain the delay between the initiation of metformin treatment and the onset of vitamin B12 deficiency

The body cannot synthesise vitamin B12 independently and must obtain it through dietary sources, primarily animal products such as meat, fish, dairy, and eggs