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Description
Under physiological conditions, the IRS undergoes tyrosine phosphorylation

Age-related changes include reduced gastric acid production (hypochlorhydria or achlorhydria), which impairs the release of B12 from food proteins

Elevations indicate a glutathione deficiency or an increased demand for glutathione production, respectively
Neurodegeneration and AD Increased presence and activity of astrocytic Cx43 hemichannels seems to be a common feature of all major neurodegenerative pathologies, including AD, PD, HD, ALS and MS 482,483,484,485,486,487
