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Description
Additionally, cancer cells carrying a mutant TP53 protein exhibit increased CHAC1 levels and show greater resistance to ferroptosis (Mehta et al., 2022)
However, in the case of iron overload, the uptake of non-transferrin-bound iron (NTBI) increases, mediated by metal transport proteins such as SLC39A14
Data are expressed as means SE
However, the use of different disease models leads to variations in research outcomes, posing a challenge for the translation of research on the relationship between ferroptosis and renal fibrosis into clinical applications
