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Notably, a critical vicious cycle forms between macrophages and fibroblasts, macrophages induce IL-6 secretion from fibroblasts via P2rx4 signaling, which further upregulates Arg1 expression in macrophages

The impact of ALA treatment on the various outcome measures monitored in the two studies indicates the magnitude of the contribution oxidative stress makes to the pathogenesis of glaucoma

PTM thanks U.G.C
