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This complete absence of tolerability-driven discontinuations represents a remarkable safety finding and indicates that even when mild side effects occurred, they were sufficiently manageable that participants chose to continue treatment

Animal studies on obesity The most compelling data comes from studies in diet-induced obese mice

In laboratory investigations, researchers found that NNMT overexpression correlates with obesity and metabolic dysfunction, while its inhibition produces remarkable metabolic benefits

Long-term human safety data does not exist