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doi: 10.1111/micc.12362 97 ThirunavukkarasuMPradeepSRUkaniGAbunnajaSYoussefMAccorsiDet al

This extraordinary potency arises from the combination of the D-phenylalanine substitution at position 7, which confers enzymatic resistance and enhanced receptor binding geometry, the Nle substitution at position 4 that prevents methionine oxidation, and the cyclic lactam constraint that pre-organizes the pharmacophore into the bioactive conformation

With intact capsules formed cheeses contains more enzymatic end products significantly than the acquired by enzyme addition directly [216, 217]

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