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FIGURE 3 Vitamin B12 Inhibited Microtubule Damage Through ER Stress After TBI Numerous studies have indicated that vitamin B12 has neuroprotective effects on TBI (Figure 4AC, the expressions of MAP-2 and Tau decreased after injury, and the Tau expression was significantly higher in the vitamin B12-treated group relative to the TBI group after 7 days

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The cerebral vasculature are formed exclusively due to the angiogenic sprouting of vessels from the perineural vascular plexus, so the process of angiogenesis plays a special and important role in the development and functioning of the CNS (Sajib, et al