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Summary of representative interventions targeting mitochondrial metabolism, dynamics, mitophagy, and mitochondrial transfer, along with their molecular mechanisms, primary target cell types, and reported effects on scar formation and neural repair after spinal cord injury

Tirzepatide before and after data from clinical trials suggests the lean mass loss percentage may be lower than with some other interventions, but it is still a legitimate concern

Clinically substantial extrathyroidal complications might result from the interaction of autoreactive immune cells and TRAb with TSHR, which is also expressed in non-thyroidal tissues such fibroblasts and adipocytes

doi: 10.1152/jappl.1999.87.5.1741