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Commensal bacteria-derived extracellular vesicles suppress ulcerative colitis through regulating the macrophages polarization and remodeling the gut microbiota

For instance, GSTP1, a specific subtype of the GST family, forms a GSTP1-JNK complex, preventing its phosphorylation under normal, non-stressed conditions

IVIG mediates its immunomodulatory action by suppressing autoantibody activity, modulating cytokine networks, inhibiting complement activation, and regulating Fc receptor expression on immune cells [100102]

rather, it is more likely that the effect is the result of the actions of multiple carcinogenic pathways working in combination