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Description
These are mainly hydrophobic molecules, but also have hydrophilic hydroxyl groups
This results in a trans configuration of the double bonded carbons

Figure 3 4 Cirrhosis-related non-cholestatic pruritus 4.1 Prevalence and mechanisms Pruritus linked to liver ailments is particularly pronounced in chronic cholestatic liver conditions like primary biliary cholangitis and primary sclerosing cholangitis

Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice