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Henceforth, these two compensating mechanisms can induce the expression of serine synthesis genes, including PHGDH (57) (Supplementary Figure 1)

IV therapy helps restore fluid levels quickly by delivering hydration directly into the bloodstream

The SELECT trial (2023) further established semaglutides cardiovascular benefits, showing a 20% reduction in major adverse cardiovascular events in overweight adults with established heart disease even without diabetes

As a result, there is an increase in adenosine and GABA activity [73]
