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Description
JBSNF-000088 binds to the active site on NNMT and leads to the demethylation of SAM to SAH ( JBSNF-000028 (Ruf et al., 2022) and JBSNF-000088 ( JBSNF-000265 was discovered through Structure-Activity Relationship (SAR) studies (Ruf et al., 2018) as a compound that binds to NNMT in a manner similar to that of NAM
BPC-157 is not FDA-approved as a drug
Typical daily dose: 2,330 mcg (2.33 mg) total blend once daily for 4 weeks, then 24 weeks off
Xu, Y., Buikema, H., van Gilst, W
