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Few studies stratify participants by biological signatures such as mitochondrial phenotypes, redox profiles, or folate receptor alpha autoantibodies, even though data indicate differential responsiveness to targeted interventions in defined endophenotypes (Frye et al., 2024
Drug Metabolism and Disposition 43 (10):14991504 Talevi A (2016) The importance of bioactivation in computer-guided drug repositioning
These effects can lead to damage to cells and tissues, further burdening the liver and other organs involved in detoxification
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