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The continuous systemic inflammation generated by this vascular damage further depletes the body's already compromised antioxidant reserves, perpetuating the cycle of chronic illness and making recovery incredibly difficult without targeted biochemical intervention

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Its the storage phase not the act of reconstitution that raises concerns about room temperature, since prolonged exposure outside refrigeration accelerates degradation and shortens the solutions usable window

In vivo, emodin potentiated the antitumor effects of paclitaxel in A549 xenografts without significant side effects, suggesting a promising combinational strategy for NSCLC treatment [481]