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A microplate reader (Synergy Mx, Biotek Instruments Inc., Winooski, VT, USA) were used for determination of all activities and scaled down for semi-high throughput to obtain linear time and protein concentration dependence

While results may vary from person to person, noticeable improvements in skin tone and texture can typically be observed within a few weeks of consistent usage

Despite hundreds of studies in the last few decades, no clear recommendations are available for cancer prevention and treatment (368)

Clinical Application For patients with melasma, solar lentigines, or post-inflammatory hyperpigmentation (PIH), I recommend incorporating a daily topical antioxidant serum containing Vitamin C, paired with a skin-brightening agent like Arbutin