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Walker, R.D., Stein, G

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In EGF-stimulated CRC cells, fidarestat potentiated EGF-induced Nrf2 and upregulated the expression of peroxisome proliferator-activated receptor gamma coactivator (PGC)-1alpha, transcription factor A, mitochondrial (TFAM), and COX-IV and attenuated DNA damage as seen by decreased levels of 8-hydroxy-2'-deoxyguanosine