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The structural modification substituting a hydroxyl group where MT-II carries an amide was designed during Palatin Technologies' development program to concentrate therapeutic effects at MC3R and MC4R while stripping out the tanning and dermatological risk that come with strong MC1R agonism

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Eiden RD, Schuetze P, Colder CR, Veira Y (2011) Maternal cocaine use and mother-toddler aggression

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