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Intervention studies using B-12 in ASD children have consistently demonstrated biochemical improvement
Lactobacillus , particularly Lactobacillus murinus , whose abundance increases significantly following metformin treatment, has been shown to mitigate intestinal barrier dysfunction and lipid peroxidation [24, 28]
On the other hand, common neurological diseases, e.g., Alzheimers disease have pronounced both marked sex-dependency (Ferretti et al., 2018) and involvement in the BBB decline (Zenaro et al., 2017)
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