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Hydrogen peroxide, which is an essential factor for thyroid hormone biosynthesis, is produced in the thyroid gland by two isoform enzymes, i.e., dual oxidase 1 (DUOX1) and 2 (DUOX2), belonging to NOX family, with the most convincing experimental evidence found for DUOX2 [137,138,139]

10.1016/j.jep.2020.112917 101 LinQ.LiS.JinH.CaiH.ZhuX.YangY.et al (2023)

Fatty acid composition of the postmortem corpus callosum of patients with schizophrenia, bipolar disorder, or major depressive disorder

Mechanistically, nitric oxide synthase (NOS) converts arginine, NADPH, and oxygen into nitric oxide, which inhibits apoptosis by altering cellular redox states (50, 51)
